Januvia (Sitagliptin) Drug Information

  • Why is this medication prescribed?

    Januvia (sitagliptin) is used along with diet and exercise and sometimes with other medications to lower blood sugar levels in patients with type 2 diabetes (condition in which blood sugar is too high because the body does not produce or use insulin normally). Januvia (sitagliptin) is in a class of medications called dipeptidyl peptidase-4 (DPP-4) inhibitors. It works by increasing the amounts of certain natural substances that lower blood sugar when it is high.

  • How should this medicine be used?

    Januvia (sitagliptin) comes as a tablet to take by mouth. It is usually taken once a day with or without food. Take Januvia (sitagliptin) at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Januvia (sitagliptin) exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

    Januvia (sitagliptin) helps to control high blood sugar but does not cure diabetes. Continue to take Januvia (sitagliptin) even if you feel well. Do not stop taking Januvia (sitagliptin) without talking to your doctor.

    Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.

  • Other uses for this medicine

    This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

  • What special precautions should I follow?

    Before taking Januvia (sitagliptin),

    • tell your doctor and pharmacist if you are allergic to Januvia (sitagliptin) or any other medications.
    • tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: digoxin (Lanoxicaps, Lanoxin); insulin; and certain oral medications for diabetes including acetohexamide, chlorpropamide (Diabinese), glimepiride (Amaryl), glipizide (Glucotrol, in Metaglip), glyburide (Diabeta, Glycron, Micronase), tolazamide (Tolinase), and tolbutamide. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
    • tell your doctor if you drink or have ever drunk large amounts of alcohol and if you have or have ever had diabetes , diabetic ketoacidosis (a serious condition that may occur when blood sugar is too high), pancreatitis (swelling of the pancreas), gallstones, high levels of triglycerides (fatty substances) in your blood, or kidney disease.
    • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking Januvia (sitagliptin), call your doctor.
    • if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking Januvia (sitagliptin).
    • talk to your doctor about what you should do if you get hurt or if you develop a fever or infection. These conditions may affect your blood sugar.
    • talk to your doctor about the symptoms of high and low blood sugar and other complications of diabetes, what to do if you develop these symptoms, and how to prevent these conditions.
  • What special dietary instructions should I follow?

    Be sure to follow all diet and exercise recommendations made by your doctor or dietician.

  • What should I do if I forget a dose?

    Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

  • What side effects can this medication cause?

    Januvia (sitagliptin) may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • stuffed or runny nose
    • sore throat
    • headache
    • diarrhea

    Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:

    • ongoing pain, that begins in the upper left or middle of the stomach but may spread to the back
    • nausea
    • vomiting
    • loss of appetite

    Januvia (sitagliptin) may cause severe or life-threatening inflammation of the pancreas. Talk to your doctor about the risks of taking this medication.

    Januvia (sitagliptin) may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

  • What storage conditions are needed for this medicine?

    Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

  • In case of emergency/overdose

    In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

  • What other information should I know?

    Keep all appointments with your doctor and the laboratory. Your blood sugar and glycosylated hemoglobin (HbA1c) should be checked regularly to determine your response to Januvia (sitagliptin). Your doctor will also tell you how to check your response to Januvia (sitagliptin) by measuring your blood or urine sugar levels at home. Follow these instructions carefully.

    Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

    It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

  • Brand Names

    • Januvia®